The League of Women Voters of Wayland is currently led by a group of members who work together to plan events. In the past, LWVW has also been led by presidents of the chapter. The leadership list is below.
| Name (President/ Executive Committee) | Term | Other |
| Caroline Whiteside | 1948-51 | |
| Peggy Bruce | 1951-53 | Became president of LWVMA |
| Mary Lou Howard | 1953-54 | |
| Jo Bertelsen (Wilson) | 1954-57 | Many other activities |
| Pat Ericksen | 1957-59 | |
| Margaret Flanagan | 1959-61 | Teacher |
| Joanne Davis | 1961-63 | Teacher |
| Sema Faigen | 1963-65 | School committee, Finance Committee, Personnel Board |
| Laura White | 1965-67 | Executive director of LWVMA |
| Katy Seiler | 1967-69 | First woman Selectmen |
| Beryl Jacobson | 1969-71 | |
| Marty Whidden | 1971 | |
| Bunny Jones | 1971-73 | |
| Barbara Leith | 1973-75 | |
| Susan Etelman | 1975-77 | |
| Bernice Samelson | 1977 | Finance Committee, WayBus |
| Sandy Hoyt | 1977-79 | School Committee |
| Nancy Carapezza | 1979-81 | Became president of LWVMA |
| Mary Antes | 1981-83 | Selectman, Housing Authority, COA |
| Jane Miles | 1983-85 | |
| Ann Hardenbergh, Jean Pratt, Ann Hamilton | 1985-86 | Jean = Zoning Board of Appeals |
| Jean Halvorson | 1986-87 | |
| Barbara Bowens | 1987-88 | |
| Judy Schurgin | 1988-90 | |
| Jamie Stern, Anna Laura Rosow | 1990-91 | Anna Laura = CAPA |
| Anna Laura Rosow | 1991-94 | |
| Sally Brotman, Patricia Cochran, Laura White, Shirley Pollitt, Amy Roberts | 1994-95 | |
| Anita Muchmore, Shirley Pollitt, Amy Roberts, Sonja Strong, Laura White | 1995-96 | |
| Amy Roberts, Sonja Strong, Laura White | 1996-97 | |
| Dorothy Bourassa | 1997-98 | |
| Shirley Pollitt, Laura White | 1999-2000 | |
| Karen Dale | 2001-2 | |
| Iryna Priester | 2002-3 | Planning Board, Board of Selectmen |
| Sonja Strong, Karen Kavet, Iryna Priester, Karen Dale, Megan Lucier, Jo Wilson | 2003-05 | |
| Karen Dale, Karen Kavet, Iryna Priester, Megan Lucier, Sonja Strong, Jo Wilson | 2005-06 | |
| Mary Antes, Nancy Carapezza, Karen Kavet (treasurer), Sema Faigen, Jean Pratt, Ginny Steel, Karen Krowne, Jane Sciacca (1 year), Elaine Sweeney (1 year), Heather Ryan (began 2013), Iryna Priester | 2006- |
League of Women Voters of Wayland 